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  • Pyung Ok Lim
  • Professor
  • +82-53-785-1830
  • polimdgist.ac.kr

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  • Information
  •  


    Research Interests



    Aging and programmed cell death in plants
    RNA-based regulation of leaf aging
    Synthetic genetics-based aging reprogramming


     


     


    ◆ Education


    1991, Michigan State University, Ph. D. in Genetics
    1985, Sogang University, M.S. in Biology
    1982, Sognag University, B. S. in Biology


     


    ◆ Professional Experience


    2012.09 - Present : Associate Professor, DGIST, Korea
    2005.03 - 2012. 08 : Assistant Professor, Associate Professor, Jeju National University


     


    Laboratory for Complex Biology



     


    Introduction to Research


    Aging in leaves is critical for plant’s fitness as nutrient relocalization from leaves to reproducing seeds is achieved through this process.
    Aging process in plants involves a coordinated action at the cellular, tissue, organ, and organism levels under the control of a highly regulated genetic program.
    We are taking systems biology approach to obtain insights into age-associated complex regulatory networks and understand the aging process in leaves.
    Synthetic genetic approaches are also taken to reprogram leaf aging based on the key regulatory network for increased biomass.
     


     



     


     


    Research Publication(selected)


    1. Kang HG, Kim J, Kim B, Jeong H, Choi SH, Kim EK, Lee HY, Lim PO (2011) Overexpression of FTL1/DDF1, an AP2 transcription factor, enhances tolerance to cold, drought, and heat stresses in Arabidopsis thaliana. Plant Science 180(4):634-641.
    2.  Woo HR, Kim JH, Kim JY, Kim JS, Lee U, Song IJ, Kim JH, Lee HY, Nam HG, Lim PO (2010) The RAV1 transcription factor positively regulates leaf senescence in  Arabidopsis. J Exp Bot. 61(14):3947–3957.
    3.  Lim PO, Lee IC, Kim J, Kim HJ, Ryu JS, Woo HR, Nam HG (2010) Auxin response factor 2 (ARF2) plays a major role in regulating auxin-mediated leaf longevity. J Exp Bot. 61(5):1419-1430.
    4.  Kim JH, Woo HR, Kim J, Lim PO, Lee IC, Choi SH, Hwang D, Nam HG (2009) Trifurcate feed-forward regulation of age-dependent cell death involving miR164 in Arabidopsis. Science. 323:1053-1057.
    5.  Lim PO, Kim Y, Breeze E, Koo JC, Woo HR, Ryu JS, Park DH, Beynon J, Tabrett A, Buchanan-Wollaston V, Nam HG. (2007) Overexpression of a chromatin architecture-controlling AT-hook protein extends leaf longevity and increases the post-harvest storage life of plants. Plant J. 52(6):1140-53.


     


    Invited Review Articles


    1.  Lim PO et al. (2007) Leaf senescence. Annu Rev Plant Biol. 58:115-36
    2.  Lim PO et al. (2003) Molecular genetics of leaf senescence in Arabidopsis. Trends in Plant Science 8:272-278.


     


    Patents(selected)
    1. Nam HG, Lim PO, Cho SH, ORE7, Gene controlling life span of leaves in plants and method for controlling life span of plants using the same. PCT/KR02/01578, China 02816505.5, CN 1547589A, Europe 02758930.8, EP1 436 324, Australia 02 758 930.8, USA 10/487,225, US-2005-0055745-A1, Reg No. 7,060,875

  • Hye Ryun Woo
  • Professor
  • +82-53-785-1831
  • hrwoodgist.ac.kr

Detail

  • Information
  • Research Interests



     Genome biology
     Epigenomics in plants
     Plant senescence


     


     


    ◆ Education


    2002: POSTECH (Ph.D. in Life Science)
    1999: POSTECH (M.S. in Life Science)
    1997: POSTECH (B.S. in Life Science)


     


    ◆ Professional Experience


    2013~present: Assistant Professor, DGIST, Korea 
    2009~2012: Assistant Professor, Dept. of Biology, Chungnam National University, Korea


     


    Major in New Biology



    Introduction to Research


    Multi-dimensional analysis of Arabidopsis transcriptome leaf across the lifespan
    Epigenomic analysis of Arabidopsis leaf lifespan


     



     


     Research Publication(selected)


    1. Yoonkang Hur, Jin Hee Kim, Dong-Joon Lee, Kyung Min Chung, and Hye Ryun Woo. Overexpression of AtCHX24, a member of the cation/H+ exchangers, accelerates leaf senescence in Arabidopsis thaliana (2012). Plant science 183, 175-182.
    2. Tae Hee Lee, Young Ran Kim, Joon Haeng Rhee, Jin-Hong Kim, Hye Ryun Woo, and Kyung Min Chung. Characterization of monoclonal antibodies targeting the RtxA1 toxin of Vibrio vulnificus (2011). Process Biochem 46, 1500-1508.
    3. Hye Ryun Woo, Jin Hee Kim, Junyoung Kim, Jeongsik Kim, Ung Lee, In-Ja Song, Jin-Hong Kim, Hyo-Yeon Lee, Hong Gil Nam and Pyung Ok Lim. The RAV1 transcription factor positively regulates leaf senescence in Arabidopsis (2010). J Exp Bot. 61(14), 3947-3957.
    4. Pyung Ok Lim, In Chul Lee, Junyoung Kim, Hyo Jung Kim, Jong Sang Ryu, Hye Ryun Woo* and Hong Gil Nam*. Auxin response factor 2 (ARF2) plays a major role in regulating auxin-mediated leaf longevity (2010). J Exp Bot. 61(5), 1419-1430. (*Corresponding authors)
    5. Jin Hee Kim*, Hye Ryun Woo*, Jeongsik Kim, Pyung Ok Lim, In Chul Lee, Seung Hee Choi, Daehee Hwang and Hong Gil Nam. Trifurcate feed-forward regulation of age-dependent cell death involving miR164 in Arabidopsis (2009). Science 323, 1053-1057. (*These authors contributed equally to this work.)

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